human SP100 shRNA silencing Adenovirus

Name
Ad-h-SP100-shRNA

Cat No
shADV-224036

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human SP100.

shADV-224036

Ad-h-SP100-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SP100 (SP100 nuclear antigen). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

lysp100b

Description (Vector)

SP100 encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.

Gene ID

6672

Gene Name (Vector)

SP100 nuclear antigen

Gene Symbol

SP100

HGNC ID

HGNC:11206

ORF Size (aa)

1443

ORF Size (bp)

1443 bp

RefSeq ID

NM_003113

RefSeq Synonyms

NM_003113, NM_001206704, NM_001206703, NM_001206702, NM_001206701, NM_001080391, BC011562,

Species

human

UniGene ID

Hs.369056

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.