human XRCC6 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-227929
Availability:
4-5 weeks
Name:
AAV-h-XRCC6-shRNA
This is an AAV expressing shRNA for silencing of Human XRCC6.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- XRCC6
- Gene Name
- X-ray repair cross complementing 6
- Gene ID
- 2547
- Gene Synonyms
- CTC75; CTCBF; G22P1; KU70; ML8; TLAA
- ORF Size
- 1830 bp
- RefSeq#
- NM_001469
- Gene Description
- The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
- UniGene ID
- Hs.292493
- HGNC ID
- HGNC:4055
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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