human SMPD1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SMPD1.
shADV-223767
Ad-h-SMPD1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SMPD1 (sphingomyelin phosphodiesterase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ASM; ASMASE; NPD
Description (Vector)
SMPD1 is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.
Gene ID
6609
Gene Name (Vector)
sphingomyelin phosphodiesterase 1
Gene Symbol
SMPD1
HGNC ID
HGNC:11120
ORF Size (aa)
1095
RefSeq ID
NM_000543
RefSeq Synonyms
NM_001318088, NM_001318087, NM_001007593, NM_000543, BC041164,
Species
human
UniGene ID
Hs.498173
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.