human SMG5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SMG5.
shADV-223753
Ad-h-SMG5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SMG5 (SMG5, nonsense mediated mRNA decay factor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EST1 telomerase component homolog B; EST1B; EST1-like protein B; Est1p-like protein B; ever shorter telomeres 1B; hSMG-5; LPTS interacting protein; LPTS-interacting protein; LPTSRP1; LPTS-RP1; protein SMG5; SMG-5; SMG-5 homolog; smg-5 homolog, nonsense mediated mRNA decay factor
Description (eCommerce)
SMG5 (Suppressor with Morphogenetic Effects on Genitalia 5) Plays a role in nonsense-mediated mRNA decay. SMG5 promotes dephosphorylation of RENT1 and is necessary for TERT activity [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9UPR3].
Description (Vector)
SMG5 is involved in nonsense-mediated mRNA decay (Ohnishi et al., 2003 (PubMed 14636577)).(supplied by OMIM, Mar 2008)
Gene ID
23381
Gene Name (eCommerce)
SMG5, nonsense mediated mRNA decay factor
Gene Name (Vector)
SMG5, nonsense mediated mRNA decay factor
Gene Symbol
SMG5
HGNC ID
HGNC:24644
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3051
ORF Size (bp)
3051 bp
Protein Name (eCommerce)
Protein SMG5
RefSeq ID
NM_015327
RefSeq Synonyms
NM_015327, NM_001323617, NM_001323616, NM_001323615, NM_001323614, BC038296,
Research Areas
Gene Expression,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
SMG5 (Suppressor with Morphogenetic Effects on Genitalia 5) Plays a role in nonsense-mediated mRNA decay. SMG5 promotes dephosphorylation of RENT1 and is necessary for TERT activity [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9UPR3].
UniGene ID
Hs.516837
UniProt ID (eCommerce)
Q9UPR3
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.