mouse SMG5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Smg5.
shADV-272643
Ad-m-SMG5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Smg5 (Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BC024683; mKIAA1089
Description (Vector)
Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.
Gene ID
229512
Gene Name (Vector)
Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)
Gene Symbol
Smg5
ORF Size (aa)
2109
ORF Size (bp)
2109 bp
RefSeq ID
NM_178246
RefSeq Synonyms
NM_178246, BC100408, BC024683,
Species
mouse
UniGene ID
Mm.439830
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.