human MAFG Over-expression AAV

Name
AAV-h-MAFG

Cat No
AAV-214797

Availability
4-5 weeks

This is an AAV expressing Human MAFG.

AAV-214797

AAV-h-MAFG

Ready-to-use AAV expressing Human MAFG (MAF bZIP transcription factor G). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

hMAF

Description (Vector)

Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 (PubMed 9166829)). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).(supplied by OMIM, Mar 2010)

Gene ID

4097

Gene Name (Vector)

MAF bZIP transcription factor G

Gene Symbol

MAFG

HGNC ID

HGNC:6781

ORF Size (aa)

489

RefSeq ID

NM_002359

RefSeq Synonyms

NM_032711, NM_002359, BC012327,

Species

human

UniGene ID

Hs.252229

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.