human SI shRNA silencing Adenovirus

Name 
Ad-h-SI-shRNA
Cat No 
shADV-222974
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human SI.

shADV-222974
Ad-h-SI-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SI (sucrase-isomaltase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
SI encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.
Gene ID
6476
Gene Name (Vector)
sucrase-isomaltase
Gene Symbol
SI
HGNC ID
HGNC:10856
ORF Size (aa)
5484
ORF Size (bp)
5484 bp
RefSeq ID
NM_001041
RefSeq Synonyms
NM_001041, BC132860, BC132834, BC116452, BC115034,
Species
human
UniGene ID
Hs.429596

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.