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human SHOC2 shRNA silencing Adenovirus

Name 
Ad-h-SHOC2-shRNA
Cat No 
shADV-222956
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human SHOC2.

shADV-222956
Ad-h-SHOC2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SHOC2 (SHOC2, leucine rich repeat scaffold protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
SIAA0862; SOC2; SUR8
Description (Vector)
SHOC2 encodes a protein that consists almost entirely of leucine-rich repeats, a domain implicated in protein-protein interactions. The protein may function as a scaffold linking RAS to downstream signal transducers in the RAS/ERK MAP kinase signaling cascade. Mutations in this gene have been associated with Noonan-like syndrome with loose anagen hair.
Gene ID
8036
Gene Name (Vector)
SHOC2, leucine rich repeat scaffold protein
Gene Symbol
SHOC2
HGNC ID
HGNC:15454
ORF Size (aa)
1749
ORF Size (bp)
1749 bp
RefSeq ID
NM_007373
RefSeq Synonyms
NM_007373, NM_001324337, NM_001324336, NM_001269039, BC050445,
Species
human
UniGene ID
Hs.104315

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.