mouse SHOC2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Shoc2.
shAAV-271960
AAV-m-SHOC2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Shoc2 (soc-2 (suppressor of clear) homolog (C. elegans)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AU017287; mKIAA0862; Sur8
Description (Vector)
Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.
Gene ID
56392
Gene Name (Vector)
soc-2 (suppressor of clear) homolog (C. elegans)
Gene Symbol
Shoc2
ORF Size (aa)
1575
ORF Size (bp)
1575 bp
RefSeq ID
NM_019658
RefSeq Synonyms
NM_019658, NM_001168505, BC083060, BC049775, BC026364,
Species
mouse
UniGene ID
Mm.228669
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.