human SFRS5 shRNA silencing Adenovirus

Name 
Ad-h-SFRS5-shRNA
Cat No 
shADV-222809
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human SRSF5.

shADV-222809
Ad-h-SFRS5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SRSF5 (serine and arginine rich splicing factor 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HRS; SFRS5; SRP40
Description (Vector)
SRSF5 is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein have been found for this gene.
Gene ID
6430
Gene Name (Vector)
serine and arginine rich splicing factor 5
Gene Symbol
SRSF5
HGNC ID
HGNC:10787
ORF Size (aa)
819
RefSeq ID
NM_006925
RefSeq Synonyms
NM_006925, NM_001320214, NM_001039465, BC040209, BC018823,
Species
human
UniGene ID
Hs.632326

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.