human SEPW1 shRNA silencing Adenovirus

Name 
Ad-h-SEPW1-shRNA
Cat No 
shADV-222621
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human SELENOW.

shADV-222621
Ad-h-SEPW1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SELENOW (selenoprotein W). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
selW; SEPW1
Description (Vector)
SEPW1 encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein shows highest expression in skeletal muscle and heart, and may be involved in oxidation-reduction reactions. A retroprocessed pseudogene, SEPW1P, has been identified and mapped to chromosome 1p35-34.
Gene ID
6415
Gene Name (Vector)
selenoprotein W
Gene Symbol
SELENOW
HGNC ID
HGNC:10752
ORF Size (aa)
264
RefSeq ID
NM_003009
RefSeq Synonyms
NM_003009, BC047893, BC039597, BC032546, BC000581,
Species
human
UniGene ID
Hs.631549

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.