human SENP2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SENP2.
shADV-222574
Ad-h-SENP2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SENP2 (SUMO1/sentrin/SMT3 specific peptidase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AXAM2; sentrin (SUMO1) specific peptidase 2; sentrin/SUMO-specific protease SENP2; sentrin-specific protease 2; SMT3IP2; SMT3-specific isopeptidase 2; SUMO1/sentrin/SMT3 specific peptidase 2; SUMO1/sentrin/SMT3 specific protease 2
Description (eCommerce)
Sentrin-specific protease 2 catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SENP2 may play a role in down-regulating CTNNB1 levels and thereby modulate the Wnt pathway [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9HC62].
Description (Vector)
SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.(supplied by OMIM, Apr 2004)
Gene ID
59343
Gene Name (eCommerce)
SUMO specific peptidase 2
Gene Name (Vector)
SUMO1/sentrin/SMT3 specific peptidase 2
Gene Symbol
SENP2
HGNC ID
HGNC:23116
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1770
ORF Size (bp)
1770 bp
Protein Name (eCommerce)
Sentrin-specific protease 2
RefSeq ID
NM_021627
RefSeq Synonyms
NM_021627, BC040609,
Research Areas
mRNA transport,RNA Transport,Signal Transduction,Wnt Signaling
Research Areas (Faceted)
cell_biology,genetics,signal_transduction,transcription_translation
Species
human
Target Sentence
Sentrin-specific protease 2 catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SENP2 may play a role in down-regulating CTNNB1 levels and thereby modulate the Wnt pathway [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9HC62].
UniGene ID
Hs.401388
UniProt ID (eCommerce)
Q9HC62
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.