human LXN Over-expression AAV

Name 
AAV-h-LXN
Cat No 
AAV-214682
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human LXN.

AAV-214682
AAV-h-LXN

Ready-to-use AAV expressing Human LXN (latexin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ECI; endogenous carboxypeptidase inhibitor; latexin; MUM; Protein MUM; TCI; tissue carboxypeptidase inhibitor
Description (eCommerce)
Latexin (LXN) is a hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA. LXN may play a role in inflammation. [taken from NCBI Entrez Gene (Gene ID: 56925)]. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BS40].
Description (Vector)
LXN encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases.
Gene ID
56925
Gene Name (eCommerce)
latexin
Gene Name (Vector)
latexin
Gene Symbol
LXN
HGNC ID
HGNC:13347
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
669
Protein Name (eCommerce)
Latexin
RefSeq ID
NM_020169
RefSeq Synonyms
NM_020169, BC008438, BC005346,
Research Areas
Immunology
Research Areas (Faceted)
immunology
Species
human
Target Sentence
Latexin (LXN) is a hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA. LXN may play a role in inflammation. [taken from NCBI Entrez Gene (Gene ID: 56925)]. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BS40].
UniGene ID
Hs.478067
UniProt ID (eCommerce)
Q9BS40

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.