human LSS Over-expression AAV

Name 
AAV-h-LSS
Cat No 
AAV-214654
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human LSS.

AAV-214654
AAV-h-LSS

Ready-to-use AAV expressing Human LSS (lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CTRCT44; OSC
Description (Vector)
LSS catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
4047
Gene Name (Vector)
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
Gene Symbol
LSS
HGNC ID
HGNC:6708
ORF Size (aa)
2199
ORF Size (bp)
2199 bp
RefSeq ID
NM_001001438
RefSeq Synonyms
NM_002340, NM_001145437, NM_001145436, NM_001001438, BC035638,
Species
human
UniGene ID
Hs.596543

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.