human RELN shRNA silencing Adenovirus

Name 
Ad-h-RELN-shRNA
Cat No 
shADV-220999
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RELN.

shADV-220999
Ad-h-RELN-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RELN (reelin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ETL7; LIS2; PRO1598; RL
Description (Vector)
RELN encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined.
Gene ID
5649
Gene Name (Vector)
reelin
Gene Symbol
RELN
HGNC ID
HGNC:9957
ORF Size (aa)
10374
ORF Size (bp)
10374 bp
RefSeq ID
NM_005045
RefSeq Synonyms
NM_173054, NM_005045, BC172269,
Species
human
UniGene ID
Hs.655654

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.