human RDH5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RDH5.
shADV-220967
Ad-h-RDH5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RDH5 (retinol dehydrogenase 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
9cRDH; HSD17B9; RDH1; SDR9C5
Description (Vector)
RDH5 encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene.
Gene ID
5959
Gene Name (Vector)
retinol dehydrogenase 5
Gene Symbol
RDH5
HGNC ID
HGNC:9940
ORF Size (aa)
957
RefSeq ID
NM_002905
RefSeq Synonyms
NM_002905, NM_001199771, BC028298,
Species
human
UniGene ID
Hs.600940
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.