human RBX1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RBX1.
shADV-220928
Ad-h-RBX1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RBX1 (ring-box 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BA554C12.1; E3 ubiquitin-protein ligase RBX1; E3 ubiquitin-protein transferase RBX1; Protein ZYP; Rbx1; regulator of cullins 1; RING finger protein 75; ring-box 1, E3 ubiquitin protein ligase; RING-box protein 1; RNF75; ROC1; ZYP protein
Description (eCommerce)
ROC1 (regulator of cullins 1) is also known as RBX1 (ring-box 1 E3 ubiquitin protein ligase). ROC1 interacts with cullin proteins and likely plays a role in ubiquitination processes necessary for cell cycle progression.
Description (Vector)
This locus encodes a RING finger-like domain-containing protein. The encoded protein interacts with cullin proteins and likely plays a role in ubiquitination processes necessary for cell cycle progression. This protein may also affect protein turnover. Related pseudogenes exist on chromosomes 2 and 5.
Gene ID
9978
Gene Name (eCommerce)
ring-box 1
Gene Name (Vector)
ring-box 1
Gene Symbol
RBX1
HGNC ID
HGNC:9928
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
327
Protein Name (eCommerce)
E3 ubiquitin-protein ligase RBX1
RefSeq ID
NM_014248
RefSeq Synonyms
NM_014248, BC001466,
Research Areas
Antigen Processing and Presentation,Cancer,Cell Cycle,Cytokine Signaling,DNA Damage/Repair,HIF-1 Signaling,Host-Virus Interactions,Hypoxia,Immunology,Interleukin Signaling,Kidney Cancer,Meiosis,Notch Signaling,Prolactin Signaling,Signal Transduction,TGF-beta Signaling,Ubiquitination,Wnt Signaling,Zinc-finger
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,developmental_biology,genetics,immunology,infectious_disease,signal_transduction,transcription_translation
Species
human
Target Sentence
ROC1 (regulator of cullins 1) is also known as RBX1 (ring-box 1 E3 ubiquitin protein ligase). ROC1 interacts with cullin proteins and likely plays a role in ubiquitination processes necessary for cell cycle progression.
UniGene ID
Hs.474949
UniProt ID (eCommerce)
P62877
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.