human PTPN20B shRNA silencing Adenovirus

Name 
Ad-h-PTPN20B-shRNA
Cat No 
shADV-220318
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PTPN20.

shADV-220318
Ad-h-PTPN20B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PTPN20 (protein tyrosine phosphatase, non-receptor type 20). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
bA142I17.1; bA42B19.1; CT126; PTPN20A; PTPN20B
Description (Vector)
The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes and several are mutated in human diseases. Chromosome 10q contains a segmental duplication resulting in multiple copies of the protein tyrosine phosphatase, non-receptor type 20 gene. The two nearly identical copies are designated as PTPN20A and PTPN20B. A third copy is only partially duplicated and contains a pseudogene, designated as PTPN20C. This gene encodes the more telomeric copy, PTPN20B. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
26095
Gene Name (Vector)
protein tyrosine phosphatase, non-receptor type 20
Gene Symbol
PTPN20
HGNC ID
HGNC:23423
ORF Size (aa)
678
RefSeq ID
NM_015605
RefSeq Synonyms
NM_015605, NM_001320691, NM_001320690, NM_001320689, NM_001320688, NM_001320686, NM_001320685, NM_001320684, NM_001320683, NM_001320682, NM_001320681, NM_001042365, NM_001042364, NM_001042363, NM_001042362, NM_001042361, NM_001042360, NM_001042359, NM_001042358, NM_001042357, BC141460, BC036539,
Species
human
UniGene ID
Hs.499552

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.