human PTGDS shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PTGDS.
shADV-220234
Ad-h-PTGDS-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PTGDS (prostaglandin D2 synthase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
L-PGDS; LPGDS; PDS; PGD2; PGDS; PGDS2
Description (Vector)
PTGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.
Gene ID
5730
Gene Name (Vector)
prostaglandin D2 synthase
Gene Symbol
PTGDS
HGNC ID
HGNC:9592
ORF Size (aa)
573
RefSeq ID
NM_000954
RefSeq Synonyms
NM_000954, BC005939,
Species
human
UniGene ID
Hs.446429
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.