human PSMB3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PSMB3.
shADV-220123
Ad-h-PSMB3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PSMB3 (proteasome subunit beta 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HC10-II
Description (Vector)
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Pseudogenes have been identified on chromosomes 2 and 12.
Gene ID
5691
Gene Name (Vector)
proteasome subunit beta 3
Gene Symbol
PSMB3
HGNC ID
HGNC:9540
ORF Size (aa)
618
RefSeq ID
NM_002795
RefSeq Synonyms
NM_002795, BC013008,
Species
human
UniGene ID
Hs.82793
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.