human PPHLN1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PPHLN1.
shADV-219534
Ad-h-PPHLN1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PPHLN1 (periphilin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CR; HSPC206; HSPC232
Description (Vector)
PPHLN1 is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Gene ID
51535
Gene Name (Vector)
periphilin 1
Gene Symbol
PPHLN1
HGNC ID
HGNC:19369
ORF Size (aa)
777
RefSeq ID
NM_016488
RefSeq Synonyms
NM_201515, NM_201440, NM_201439, NM_201438, NM_016488, NM_001143789, NM_001143788, NM_001143787, BC039832,
Species
human
UniGene ID
Hs.444157
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.