human PPIL5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human LRR1.
shAAV-219568
AAV-h-PPIL5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human LRR1 (leucine rich repeat protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4-1BBLRR; LRR-1; PPIL5
Description (Vector)
LRR1 contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. Alternative splicing results in multiple transcript variants.
Gene ID
122769
Gene Name (Vector)
leucine rich repeat protein 1
Gene Symbol
LRR1
HGNC ID
HGNC:19742
ORF Size (aa)
1242
ORF Size (bp)
1242 bp
RefSeq ID
NM_152329
RefSeq Synonyms
NM_203467, NM_152329, BC148859, BC146425, BC139921,
Species
human
UniGene ID
Hs.710054
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.