human PON2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PON2.
shADV-219444
Ad-h-PON2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PON2 (paraoxonase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
PON2 encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
5445
Gene Name (Vector)
paraoxonase 2
Gene Symbol
PON2
HGNC ID
HGNC:9205
ORF Size (aa)
1065
ORF Size (bp)
1065 bp
RefSeq ID
NM_000305
RefSeq Synonyms
NM_001018161, NM_000305, BC046160, BC040010,
Species
human
UniGene ID
Hs.530077
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.