human PINK1 shRNA silencing Adenovirus

Name 
Ad-h-PINK1-shRNA
Cat No 
shADV-218975
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human PINK1.

shADV-218975
Ad-h-PINK1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PINK1 (PTEN induced putative kinase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BRPK; PARK6
Description (Vector)
PINK1 encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease.
Gene ID
65018
Gene Name (Vector)
PTEN induced putative kinase 1
Gene Symbol
PINK1
HGNC ID
HGNC:14581
ORF Size (aa)
1746
ORF Size (bp)
1746 bp
RefSeq ID
NM_032409
RefSeq Synonyms
NM_032409, BC028215,
Species
human
UniGene ID
Hs.389171

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.