human PEX26 shRNA silencing Adenovirus

Name
Ad-h-PEX26-shRNA

Cat No
shADV-218642

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human PEX26.

shADV-218642

Ad-h-PEX26-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PEX26 (peroxisomal biogenesis factor 26). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

PBD7A; PBD7B; PEX26M1T; Pex26pM1T

Description (Vector)

PEX26 belongs to the peroxin-26 gene family. It is probably required for protein import into peroxisomes. It anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Defects in this gene are the cause of peroxisome biogenesis disorder complementation group 8 (PBD-CG8). PBD refers to a group of peroxisomal disorders arising from a failure of protein import into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). Alternatively spliced transcript variants have been identified for this gene.

Gene ID

55670

Gene Name (Vector)

peroxisomal biogenesis factor 26

Gene Symbol

PEX26

HGNC ID

HGNC:22965

ORF Size (aa)

918

RefSeq ID

NM_017929

RefSeq Synonyms

NM_017929, NM_001199319, NM_001127649, BC047320, BC016280,

Species

human

UniGene ID

Hs.648441

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.