human PEX26 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PEX26.
shAAV-218642
AAV-h-PEX26-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PEX26 (peroxisomal biogenesis factor 26). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PBD7A; PBD7B; PEX26M1T; Pex26pM1T
Description (Vector)
PEX26 belongs to the peroxin-26 gene family. It is probably required for protein import into peroxisomes. It anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Defects in this gene are the cause of peroxisome biogenesis disorder complementation group 8 (PBD-CG8). PBD refers to a group of peroxisomal disorders arising from a failure of protein import into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). Alternatively spliced transcript variants have been identified for this gene.
Gene ID
55670
Gene Name (Vector)
peroxisomal biogenesis factor 26
Gene Symbol
PEX26
HGNC ID
HGNC:22965
ORF Size (aa)
918
RefSeq ID
NM_017929
RefSeq Synonyms
NM_017929, NM_001199319, NM_001127649, BC047320, BC016280,
Species
human
UniGene ID
Hs.648441
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.