human PEMT shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PEMT.
shADV-218615
Ad-h-PEMT-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PEMT (phosphatidylethanolamine N-methyltransferase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PEAMT; PEMPT; PEMT2; PLMT; PNMT
Description (Vector)
Phosphatidylcholine (PC) is the most abundant mammalian phospholipid. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. Another distinct synthetic pathway in nucleated cells converts intracellular choline to phosphatidylcholine by a three-step process. The protein isoforms encoded by this gene localize to the endoplasmic reticulum and mitochondria-associated membranes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
Gene ID
10400
Gene Name (Vector)
phosphatidylethanolamine N-methyltransferase
Gene Symbol
PEMT
HGNC ID
HGNC:8830
ORF Size (aa)
711
RefSeq ID
NM_007169
RefSeq Synonyms
NM_148173, NM_148172, NM_007169, NM_001267552, NM_001267551, BC050593, BC000557,
Species
human
UniGene ID
Hs.287717
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.