human PDE4D shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PDE4D.
shADV-218479
Ad-h-PDE4D-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PDE4D (phosphodiesterase 4D). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ACRDYS2; cAMP-specific 3',5'-cyclic phosphodiesterase 4D; cAMP-specific phosphodiesterase PDE4D6; DPDE3; HSPDE4D; PDE43; PDE4DN2; phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila); STRK1; testicular tissue protein Li 136
Description (eCommerce)
PDE4D (cAMP-specific 3’,5’-cyclic phosphodiesterase 4D) is one of four mammalian counterparts to the fruit fly 'dunce' gene. PDE4D has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types [taken from NCBI Entrez Gene (GeneID: 5144)].
Description (Vector)
PDE4D encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. PDE4D uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.
Gene ID
5144
Gene Name (eCommerce)
phosphodiesterase 4D
Gene Name (Vector)
phosphodiesterase 4D
Gene Symbol
PDE4D
HGNC ID
HGNC:8783
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1557
ORF Size (bp)
1557 bp
Protein Name (eCommerce)
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
RefSeq ID
NM_006203
RefSeq Synonyms
NM_006203, NM_001197223, NM_001197222, NM_001197221, NM_001197220, NM_001197219, NM_001197218, NM_001165899, NM_001104631, BC036319, BC008390,
Research Areas
Cardiovascular,Cytoskeleton,GPCR Signaling,Metabolism/Metabolic Process,Neurobiology,Signal Transduction,TSH Signaling
Research Areas (Faceted)
cardiovascular,signal_transduction,cell_biology,metabolism,neurobiology,signal_transduction
Species
human
Target Sentence
PDE4D (cAMP-specific 3’,5’-cyclic phosphodiesterase 4D) is one of four mammalian counterparts to the fruit fly 'dunce' gene. PDE4D has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types [taken from NCBI Entrez Gene (GeneID: 5144)].
UniGene ID
Hs.117545
UniProt ID (eCommerce)
Q08499
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.