human PCK1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PCK1.
shADV-218382
Ad-h-PCK1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PCK1 (phosphoenolpyruvate carboxykinase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PEPCK-C; PEPCK1; PEPCKC
Description (Vector)
PCK1 is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
Gene ID
5105
Gene Name (Vector)
phosphoenolpyruvate carboxykinase 1
Gene Symbol
PCK1
HGNC ID
HGNC:8724
ORF Size (aa)
1869
ORF Size (bp)
1869 bp
RefSeq ID
NM_002591
RefSeq Synonyms
NM_002591, BC023978,
Species
human
UniGene ID
Hs.1872
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.