human PAPD5 shRNA silencing Adenovirus

Name 
Ad-h-PAPD5-shRNA
Cat No 
shADV-218189
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PAPD5.

shADV-218189
Ad-h-PAPD5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PAPD5 (poly(A) RNA polymerase D5, non-canonical). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
non-canonical poly(A) RNA polymerase PAPD5; PAP associated domain containing 5; PAP-associated domain-containing protein 5; PAPD5; poly(A) RNA polymerase D5, non-canonical; Terminal nucleotidyltransferase 4B; terminal uridylyltransferase 3; topoisomerase-related function protein 4-2; TRF4-2; TUT3; TUTase 3
Description (eCommerce)
Non-canonical poly(A) RNA polymerase PAPD5, also called terminal uridylyltransferase 3 (TUTase 3), is encoded for by the gene PAPD5. TUTase 3 is the catalytic subunit of a TRAMP-like complex which has poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. PAPD5 plays a role in replication-dependent histone mRNA degradation and may play a role in sister chromatid cohesion [taken from UniProtKB (Entry: Q8NDF8)].
Gene ID
64282
Gene Name (eCommerce)
terminal nucleotidyltransferase 4B
Gene Name (Vector)
poly(A) RNA polymerase D5, non-canonical
Gene Symbol
PAPD5
HGNC ID
HGNC:30758
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1326
ORF Size (bp)
1326 bp
Protein Name (eCommerce)
Non-canonical poly(A) RNA polymerase PAPD5
RefSeq ID
NM_001040285
RefSeq Synonyms
NM_001040285, NM_001040284, BC157079, BC156329,
Research Areas
Cell Biology,Cell Cycle,Cell Division,DNA Replication,mRNA Processing,RNA Processing
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
Non-canonical poly(A) RNA polymerase PAPD5, also called terminal uridylyltransferase 3 (TUTase 3), is encoded for by the gene PAPD5. TUTase 3 is the catalytic subunit of a TRAMP-like complex which has poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. PAPD5 plays a role in replication-dependent histone mRNA degradation and may play a role in sister chromatid cohesion [taken from UniProtKB (Entry: Q8NDF8)].
UniGene ID
Hs.514342
UniProt ID (eCommerce)
Q8NDF8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.