human PARG Over-expression AAV

Name 
AAV-h-PARG
Cat No 
AAV-214352
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PARG.

AAV-214352
AAV-h-PARG

Ready-to-use AAV expressing Human PARG (poly(ADP-ribose) glycohydrolase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
mitochondrial poly(ADP-ribose) glycohydrolase; PARG99; poly(ADP-ribose) glycohydrolase; poly(ADP-ribose) glycohydrolase 60 kDa isoform
Description (eCommerce)
Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. PARG is found in many tissues and may be subject to proteolysis generating smaller, active products [taken from NCBI Entrez Gene (Gene ID: 8505)].
Description (Vector)
Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products.
Gene ID
8505
Gene Name (eCommerce)
poly(ADP-ribose) glycohydrolase
Gene Name (Vector)
poly(ADP-ribose) glycohydrolase
Gene Symbol
PARG
HGNC ID
HGNC:8605
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2931
ORF Size (bp)
2931 bp
Protein Name (eCommerce)
Poly(ADP-ribose) glycohydrolase
RefSeq ID
NM_003631
RefSeq Synonyms
NM_003631, NM_001324381, NM_001303489, NM_001303487, NM_001303486, BC052966, BC050560,
Research Areas
DNA Damage/Repair,Metabolism/Metabolic Process,Mitochondrion
Research Areas (Faceted)
genetics,transcription_translation,metabolism,cell_biology
Species
human
Target Sentence
Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. PARG is found in many tissues and may be subject to proteolysis generating smaller, active products [taken from NCBI Entrez Gene (Gene ID: 8505)].
UniGene ID
Hs.535298
UniProt ID (eCommerce)
Q86W56

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.