human ORC4L shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ORC4.
shADV-217927
Ad-h-ORC4L-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ORC4 (origin recognition complex subunit 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ORC4L; ORC4P
Description (Vector)
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.
Gene ID
5000
Gene Name (Vector)
origin recognition complex subunit 4
Gene Symbol
ORC4
HGNC ID
HGNC:8490
ORF Size (aa)
1311
ORF Size (bp)
1311 bp
RefSeq ID
NM_002552
RefSeq Synonyms
NM_181742, NM_181741, NM_002552, NM_001190882, NM_001190881, NM_001190879, BC014847, BC005388,
Species
human
UniGene ID
Hs.558364
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.