human NRCAM shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NRCAM.
shADV-217072
Ad-h-NRCAM-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NRCAM (neuronal cell adhesion molecule). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
4897
Gene Name (Vector)
neuronal cell adhesion molecule
Gene Symbol
NRCAM
HGNC ID
HGNC:7994
ORF Size (aa)
3543
ORF Size (bp)
3543 bp
RefSeq ID
NM_005010
RefSeq Synonyms
NM_005010, NM_001193584, NM_001193583, NM_001193582, NM_001037132, BC115736, BC114570, BC098401,
Species
human
UniGene ID
Hs.21422
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.