human NOS2 shRNA silencing Adenovirus

Name 
Ad-h-NOS2-shRNA
Cat No 
shADV-216904
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human NOS2.

shADV-216904
Ad-h-NOS2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NOS2 (nitric oxide synthase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
hepatocyte NOS; HEP-NOS; inducible NO synthase; inducible NOS; INOS; nitric oxide synthase 2, inducible; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; NOS; NOS type II; NOS, type II; NOS2A; peptidyl-cysteine S-nitrosylase NOS2
Description (eCommerce)
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide synthase is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. [taken from NCBI Entrez Gene (Gene ID: 4843)].
Description (Vector)
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17.
Gene ID
4843
Gene Name (eCommerce)
nitric oxide synthase 2
Gene Name (Vector)
nitric oxide synthase 2
Gene Symbol
NOS2
HGNC ID
HGNC:7873
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3462
ORF Size (bp)
3462 bp
Protein Name (eCommerce)
Nitric oxide synthase, inducible
RefSeq ID
NM_000625
RefSeq Synonyms
NM_000625, BC144126, BC130283,
Research Areas
Cancer,Cardiology,Cardiovascular,Cytoskeleton,Gene Expression,HIF-1 Signaling,Hypoxia,IFN Signaling,Immunology,Innate Immunity,Interleukin Signaling,Lung Cancer,Neurobiology,Prolactin Signaling,Signal Transduction
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,immunology,neurobiology,signal_transduction
Species
human
Target Sentence
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide synthase is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. [taken from NCBI Entrez Gene (Gene ID: 4843)].
UniGene ID
Hs.709191
UniProt ID (eCommerce)
P35228

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.