human SDHC Over-expression AAV

Name 
AAV-h-SDHC
Cat No 
AAV-214170
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SDHC.

AAV-214170
AAV-h-SDHC

Ready-to-use AAV expressing Human SDHC (succinate dehydrogenase complex subunit C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CYB560; CYBL; PGL3; QPS1; SDH3
Description (Vector)
SDHC encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. Several related pseudogenes are located in different genomic regions. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
6391
Gene Name (Vector)
succinate dehydrogenase complex subunit C
Gene Symbol
SDHC
HGNC ID
HGNC:10682
ORF Size (aa)
510
RefSeq ID
NM_003001
RefSeq Synonyms
NM_003001, NM_001278172, NM_001035513, NM_001035512, NM_001035511, BC066329, BC033626, BC020808,
Species
human
UniGene ID
Hs.444472

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.