human NFKBIE shRNA silencing Adenovirus

Name 
Ad-h-NFKBIE-shRNA
Cat No 
shADV-216652
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human NFKBIE.

shADV-216652
Ad-h-NFKBIE-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NFKBIE (NFKB inhibitor epsilon). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
IKBE
Description (Vector)
NFKBIE binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus.
Gene ID
4794
Gene Name (Vector)
NFKB inhibitor epsilon
Gene Symbol
NFKBIE
HGNC ID
HGNC:7799
ORF Size (aa)
1503
ORF Size (bp)
1503 bp
RefSeq ID
NM_004556
RefSeq Synonyms
NM_004556, BC166665,
Species
human
UniGene ID
Hs.458276

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.