human MMP7 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MMP7.
shADV-215603
Ad-h-MMP7-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MMP7 (matrix metallopeptidase 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MMP-7; MPSL1; PUMP-1
Description (Vector)
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Gene ID
4316
Gene Name (Vector)
matrix metallopeptidase 7
Gene Symbol
MMP7
HGNC ID
HGNC:7174
ORF Size (aa)
804
RefSeq ID
NM_002423
RefSeq Synonyms
NM_002423, BC003635,
Species
human
UniGene ID
Hs.2256
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.