human MMP13 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MMP13.
shADV-215572
Ad-h-MMP13-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MMP13 (matrix metallopeptidase 13). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CLG3; MANDP1; MDST; MMP-13
Description (Vector)
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Gene ID
4322
Gene Name (Vector)
matrix metallopeptidase 13
Gene Symbol
MMP13
HGNC ID
HGNC:7159
ORF Size (aa)
1416
ORF Size (bp)
1416 bp
RefSeq ID
NM_002427
RefSeq Synonyms
NM_002427, BC074808, BC074807, BC067523, BC067522,
Species
human
UniGene ID
Hs.2936
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.