human METTL3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human METTL3.
shADV-215338
Ad-h-METTL3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human METTL3 (methyltransferase like 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
adoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase; hMETTL3; IME4; M6A; methyltransferase-like protein 3; mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase; mRNA m(6)A methyltransferase; MT-A70; N6-adenosine-methyltransferase 70 kDa subunit; N6-adenosine-methyltransferase catalytic subunit; Spo8
Description (eCommerce)
METTL3/MT-A70 is a subunit of the N6-methyltransferase that specifically methylates adenines in pre-mRNAs.
Description (Vector)
METTL3 encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
Gene ID
56339
Gene Name (eCommerce)
methyltransferase like 3
Gene Name (Vector)
methyltransferase like 3
Gene Symbol
METTL3
HGNC ID
HGNC:17563
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1743
ORF Size (bp)
1743 bp
Protein Name (eCommerce)
N6-adenosine-methyltransferase 70 kDa subunit
RefSeq ID
NM_019852
RefSeq Synonyms
NM_019852, BC052244, BC003031, BC001650,
Research Areas
Gene Expression,Methyltransferase,mRNA Processing,Neurobiology,RNA Binding,RNA Processing
Research Areas (Faceted)
transcription_translation,cell_biology,genetics,neurobiology
Species
human
Target Sentence
METTL3/MT-A70 is a subunit of the N6-methyltransferase that specifically methylates adenines in pre-mRNAs.
UniGene ID
Hs.168799
UniProt ID (eCommerce)
Q86U44
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.