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human MAFF shRNA silencing Adenovirus

Name 
Ad-h-MAFF-shRNA
Cat No 
shADV-214795
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human MAFF.

shADV-214795
Ad-h-MAFF-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human MAFF (MAF bZIP transcription factor F). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
81
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
hMafF; U-MAF
Description (Vector)
MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene.
Gene ID
23764
Gene Name (Vector)
MAF bZIP transcription factor F
Gene Symbol
MAFF
HGNC ID
HGNC:6780
ORF Size (aa)
495
RefSeq ID
NM_012323
RefSeq Synonyms
NM_012323, NM_001161574, NM_001161573, NM_001161572, BC067751, BC015037,
Species
human
UniGene ID
Hs.517617

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.