human LSM7 shRNA silencing Adenovirus

Name 
Ad-h-LSM7-shRNA
Cat No 
shADV-214645
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human LSM7.

shADV-214645
Ad-h-LSM7-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human LSM7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
LSM7 homolog, U6 small nuclear RNA associated; LSM7 U6 small nuclear RNA and mRNA degradation associated; U6 snRNA-associated Sm-like protein LSm7; YNL147W
Description (eCommerce)
U6 snRNA-associated Sm-like protein LSm7 is encoded by the gene LSM7. Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing [taken from NCBI Entrez Gene (Gene ID: 51690)].
Description (Vector)
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.(supplied by OMIM, Apr 2004)
Gene ID
51690
Gene Name (eCommerce)
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
Gene Name (Vector)
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
Gene Symbol
LSM7
HGNC ID
HGNC:20470
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
312
Protein Name (eCommerce)
U6 snRNA-associated Sm-like protein LSm7
RefSeq ID
NM_016199
RefSeq Synonyms
NM_016199, BC018621,
Research Areas
Gene Expression,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
U6 snRNA-associated Sm-like protein LSm7 is encoded by the gene LSM7. Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing [taken from NCBI Entrez Gene (Gene ID: 51690)].
UniGene ID
Hs.512610
UniProt ID (eCommerce)
Q9UK45

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.