human ARPP21 shRNA silencing Adenovirus

Name 
Ad-h-ARPP21-shRNA
Cat No 
shADV-214110
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ARPP21.

shADV-214110
Ad-h-ARPP21-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ARPP21 (cAMP regulated phosphoprotein 21). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ARPP-21; cAMP regulated phosphoprotein 21kDa; cAMP-regulated phosphoprotein 21; cyclic AMP-regulated phosphoprotein, 21 kD; R3H domain containing 3; R3HDM3; RCS; TARPP; thymocyte cAMP-regulated phosphoprotein
Description (eCommerce)
ARPP21 is a cAMP-regulated phosphoprotein. ARPP21 is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia [taken from NCBI Entrez Gene (Gene ID: 10777)].
Description (Vector)
ARPP21 encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia. Alternate splicing results in multiple transcript variants.
Gene ID
10777
Gene Name (eCommerce)
cAMP regulated phosphoprotein 21
Gene Name (Vector)
cAMP regulated phosphoprotein 21
Gene Symbol
ARPP21
HGNC ID
HGNC:16968
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2439
ORF Size (bp)
2439 bp
Protein Name (eCommerce)
cAMP-regulated phosphoprotein 21
RefSeq ID
NM_198399
RefSeq Synonyms
NM_198399, NM_016300, NM_001267619, NM_001267618, NM_001267617, NM_001267616, NM_001025069, NM_001025068, BC051828, BC036399,
Research Areas
Cell Biology
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
ARPP21 is a cAMP-regulated phosphoprotein. ARPP21 is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia [taken from NCBI Entrez Gene (Gene ID: 10777)].
UniGene ID
Hs.713605
UniProt ID (eCommerce)
Q9UBL0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.