human KIAA1598 shRNA silencing Adenovirus

Name 
Ad-h-KIAA1598-shRNA
Cat No 
shADV-213023
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SHTN1.

shADV-213023
Ad-h-KIAA1598-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SHTN1 (shootin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
KIAA1598; shootin1; shootin-1
Description (eCommerce)
Shootin-1 is involved in the generation of internal asymmetric signals required for neuronal polarization. It acts upstream of PI3K (phosphoinositide 3-kinase) by being required for spatially localized PI3K activity. Shootin-1 accumulates asymmetrically in a single neurite before polarization, leading to axon induction for polarization [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/A0MZ66].
Gene ID
57698
Gene Name (eCommerce)
shootin 1
Gene Name (Vector)
shootin 1
Gene Symbol
SHTN1
HGNC ID
HGNC:29319
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1677
ORF Size (bp)
1677 bp
Protein Name (eCommerce)
Shootin-1
RefSeq ID
NM_018330
RefSeq Synonyms
NM_018330, NM_001258300, NM_001258299, NM_001258298, NM_001127211, BC032303, BC022348,
Research Areas
Axon Guidance,Neurobiology
Research Areas (Faceted)
neurobiology
Species
human
Target Sentence
Shootin-1 is involved in the generation of internal asymmetric signals required for neuronal polarization. It acts upstream of PI3K (phosphoinositide 3-kinase) by being required for spatially localized PI3K activity. Shootin-1 accumulates asymmetrically in a single neurite before polarization, leading to axon induction for polarization [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/A0MZ66].
UniGene ID
Hs.501140
UniProt ID (eCommerce)
A0MZ66

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.