human KHDRBS1 shRNA silencing Adenovirus

Name 
Ad-h-KHDRBS1-shRNA
Cat No 
shADV-212872
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human KHDRBS1.

shADV-212872
Ad-h-KHDRBS1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KHDRBS1 (KH RNA binding domain containing, signal transduction associated 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
98
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GAP-associated tyrosine phosphoprotein p62; GAP-associated tyrosine phosphoprotein p62 (Sam68); KH domain containing, RNA binding, signal transduction associated 1; KH domain-containing, RNA-binding, signal transduction-associated protein 1; p21 Ras GTPase-activating protein-associated p62; p62; p68; Sam68; src-associated in mitosis 68 kDa protein
Description (eCommerce)
SAM68 (Src-associated in mitosis 68 kDa protein) was identified as an SH3 and SH2 domain interacting protein. It is a Src substrate and contains a KH-type RNA binding domain. It has been shown to function as a regulator of mRNA stability, pre-mRNA processing, and RNA export.
Gene ID
10657
Gene Name (eCommerce)
KH RNA binding domain containing, signal transduction associated 1
Gene Name (Vector)
KH RNA binding domain containing, signal transduction associated 1
Gene Symbol
KHDRBS1
HGNC ID
HGNC:18116
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1332
ORF Size (bp)
1332 bp
Protein Name (eCommerce)
KH domain-containing, RNA-binding, signal transduction-associated protein 1
RefSeq ID
NM_006559
RefSeq Synonyms
NM_006559, NM_001271878, BC019109, BC010132, BC000717,
Research Areas
Cell Cycle,EGFR Signaling,Immunology,Leptin Signaling,mRNA Processing,RNA Binding,RNA Processing,Signal Transduction,T-cell Receptor Signaling,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation,immunology,signal_transduction
Species
human
Target Sentence
SAM68 (Src-associated in mitosis 68 kDa protein) was identified as an SH3 and SH2 domain interacting protein. It is a Src substrate and contains a KH-type RNA binding domain. It has been shown to function as a regulator of mRNA stability, pre-mRNA processing, and RNA export.
UniGene ID
Hs.709204
UniProt ID (eCommerce)
Q07666

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.