human KDM5D shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human KDM5D.
shADV-212855
Ad-h-KDM5D-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human KDM5D (lysine demethylase 5D). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
epididymis secretory sperm binding protein; histocompatibility Y antigen; histone demethylase JARID1D; HY; H-Y; HYA; JARID1D; Jumonji, AT rich interactive domain 1D (RBP2-like); jumonji/ARID domain-containing protein 1D; lysine (K)-specific demethylase 5D; lysine-specific demethylase 5D; protein SmcY; selected mouse cDNA on Y, human homolog of; SMC homolog, Y chromosome; SMCY; Smcy homolog, Y-linked
Description (eCommerce)
JARID1D is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. JARID1D maps to the azoospermia factor region (AZF) on the Y chromosome and thus is also known as SMCY (selected mouse cDNA on Y chromosome) homolog. Jarid1D displays histone H3K4 demethylase activity and may have male specific functions.
Description (Vector)
KDM5D encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient. Alternative splicing results in multiple transcript variants.
Gene ID
8284
Gene Name (eCommerce)
lysine demethylase 5D
Gene Name (Vector)
lysine demethylase 5D
Gene Symbol
KDM5D
HGNC ID
HGNC:11115
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4713
ORF Size (bp)
4713 bp
Protein Name (eCommerce)
Lysine-specific demethylase 5D
RefSeq ID
NM_004653
RefSeq Synonyms
NM_004653, NM_001146706, NM_001146705, BC146767, BC144102, BC132721,
Research Areas
Cancer,Chromatin Remodeling,Histone Modification,Spermatogenesis,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cancer,cell_biology,developmental_biology,genetics,transcription_translation
Species
human
Target Sentence
JARID1D is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. JARID1D maps to the azoospermia factor region (AZF) on the Y chromosome and thus is also known as SMCY (selected mouse cDNA on Y chromosome) homolog. Jarid1D displays histone H3K4 demethylase activity and may have male specific functions.
UniGene ID
Hs.80358
UniProt ID (eCommerce)
Q9BY66
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.