human LDLRAP1 Over-expression AAV

Name 
AAV-h-LDLRAP1
Cat No 
AAV-213805
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human LDLRAP1.

AAV-213805
AAV-h-LDLRAP1

Ready-to-use AAV expressing Human LDLRAP1 (low density lipoprotein receptor adaptor protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ARH; ARH1; ARH2; FHCB1; FHCB2
Description (Vector)
LDLRAP1 is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia.
Gene ID
26119
Gene Name (Vector)
low density lipoprotein receptor adaptor protein 1
Gene Symbol
LDLRAP1
HGNC ID
HGNC:18640
ORF Size (aa)
927
ORF Size (bp)
927 bp
RefSeq ID
NM_015627
RefSeq Synonyms
NM_015627, BC029770,
Species
human
UniGene ID
Hs.590911

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.