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mouse LDLRAP1 Adenovirus

Name 
Ad-m-LDLRAP1
Cat No 
ADV-280842
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse Ldlrap1.

ADV-280842
Ad-m-LDLRAP1

Ready-to-use Adenovirus expressing Mouse Ldlrap1 (low density lipoprotein receptor adaptor protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AA691260; Arh; Arh1; ARH2; FHCB1; FHCB2
Description (Vector)
Adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). May be required for LDL binding and internalization but not for receptor clustering in coated pits. May facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits. May also be involved in the internalization of other LDLR family members. Binds to phosphoinositides, which regulate clathrin bud assembly at the cell surface.
Gene ID
100017
Gene Name (Vector)
low density lipoprotein receptor adaptor protein 1
Gene Symbol
Ldlrap1
ORF Size (aa)
927
ORF Size (bp)
927 bp
RefSeq ID
NM_145554
RefSeq Synonyms
NM_145554, BC067411, BC066808, BC021467,
Species
mouse
UniGene ID
Mm.27486

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.