human KCNE2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human KCNE2.
shADV-212685
Ad-h-KCNE2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human KCNE2 (potassium voltage-gated channel subfamily E regulatory subunit 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ATFB4; LQT5; LQT6; MIRP1
Description (Vector)
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia.
Gene ID
9992
Gene Name (Vector)
potassium voltage-gated channel subfamily E regulatory subunit 2
Gene Symbol
KCNE2
HGNC ID
HGNC:6242
ORF Size (aa)
372
RefSeq ID
NM_172201
RefSeq Synonyms
NM_172201, BC112087, BC093892,
Species
human
UniGene ID
Hs.679753
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.