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human ITGA5 shRNA silencing Adenovirus

Name 
Ad-h-ITGA5-shRNA
Cat No 
shADV-212482
Availability
Immediate

This is an Adenovirus expressing shRNA for silencing of Human ITGA5.

shADV-212482
Ad-h-ITGA5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ITGA5 (integrin subunit alpha 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD49e; FNRA; VLA-5; VLA5A
Description (Vector)
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Gene ID
3678
Gene Name (Vector)
integrin subunit alpha 5
Gene Symbol
ITGA5
HGNC ID
HGNC:6141
ORF Size (aa)
3150
ORF Size (bp)
3150 bp
RefSeq ID
NM_002205
RefSeq Synonyms
NM_002205, BC008786,
Species
human
UniGene ID
Hs.505654

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.