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human IRF5 shRNA silencing Adenovirus

Name 
Ad-h-IRF5-shRNA
Cat No 
shADV-212410
Availability
Immediate

This is an Adenovirus expressing shRNA for silencing of Human IRF5.

shADV-212410
Ad-h-IRF5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human IRF5 (interferon regulatory factor 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
92
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
SLEB10
Description (Vector)
IRF5 encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment.
Gene ID
3663
Gene Name (Vector)
interferon regulatory factor 5
Gene Symbol
IRF5
HGNC ID
HGNC:6120
ORF Size (aa)
1497
ORF Size (bp)
1497 bp
RefSeq ID
NM_001098629
RefSeq Synonyms
NM_032643, NM_001242452, NM_001098630, NM_001098629, NM_001098627, BC004201, BC004139,
Species
human
UniGene ID
Hs.521181

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.